CultureGro™ Human IL-6

Name: CultureGro™ Human IL-6 - Cell Culture Collective
SKU: CultureGro™ Human IL-6
Availability: InStock

$390.00

IL-6 is a multifaceted cytokine pivotal in host defense, orchestrating immune and inflammatory responses. It’s generated by T cells, monocytes, fibroblasts, endothelial cells, and keratinocytes, showcasing a wide array of biological functions. IL-6 promotes B cell differentiation and antibody production, collaborates with IL-3 in megakaryocyte development and platelet production, triggers the expression of hepatic acute-phase proteins, and governs bone metabolism.

IL-6 communicates through the IL-6 receptor system composed of two chains: IL-6Rα and gp130. Notably, murine IL-6 lacks activity on Human cells, while both Human and murine variants are equally effective on murine cells. The recombinant Human IL-6 is a 20.9 kDa protein encompassing 184 amino acid residues.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human IL-6 Categories Cytokines, Recombinant Proteins

Product Details

Product Specifications Species Human Published species Human, Mouse Expression System E. coli Amino acid sequence PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM Molecular weight 20.9 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by its ability to stimulate the proliferation of mouse B9 cells. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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