CultureGro™ Human BDNF

Name: CultureGro™ Human BDNF - Cell Culture Collective
SKU: CultureGro™ Human BDNF
Availability: InStock

$650.00

BDNF belongs to the NGF family of neurotrophic growth factors, supporting neuron growth and survival. It binds to a low-affinity cell surface receptor, LNGFR, shared with other neurotrophins like NGF, NT-3, and NT-4. However, BDNF primarily exerts its neurotrophic effects through the high-affinity receptor gp145/trkB. Structurally, BDNF is part of a 247 amino acid polypeptide precursor, featuring an 18 amino acid signal sequence and a 110 amino acid propeptide. Recombinant Human/Murine/Rat BDNF exists as a 27.0 kDa homodimer comprising two 120 amino acid subunits held together by robust non-covalent interactions.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human BDNF Categories Neurotrophic Growth Factors, Recombinant Proteins

Product Details

Product Specifications Species Human, Mouse, Rat Published species Amphibian, Chicken, Human, Mouse, Non-human primate, Rat Expression System E. coli Amino acid sequence MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR Molecular weight 27.0 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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