$650.00
IL-10, an immunosuppressive cytokine, is synthesized by various mammalian cell types like macrophages, monocytes, T cells, B cells, and keratinocytes. Its primary function is to dampen the expression of proinflammatory cytokines such as IL-1 and TNF-α. Similar to IL-4, IL-10 boosts humoral immune responses while tempering cell-mediated immune reactions.
Interestingly, Human IL-10 exhibits activity on murine cells, but the reverse is not true—murine IL-10 doesn’t affect Human cells. The recombinant Human IL-10, a protein weighing 18.6 kDa and comprising 161 amino acid residues, reflects these immunomodulatory properties.
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