CultureGro™ Human NT-3

Name: CultureGro™ Human NT-3 - Cell Culture Collective
SKU: CultureGro™ Human NT-3
Availability: InStock

$631.00

NT-3, a neurotrophic factor, shares structural kinship with β-NGF, BDNF, and NT-4, all part of the cysteine-knot family of growth factors known for their stable dimeric structures. It’s predominantly expressed by neurons in the central nervous system and activates signaling pathways through the trk receptors. NT-3 plays a vital role in promoting the growth and survival of both nerve cells and glial cells. Notably, the amino acid sequences of Human, murine, and rat NT-3 are identical. Recombinant Human NT-3 forms a noncovalently linked homodimer consisting of two 13.6 kDa polypeptide monomers, totaling 240 amino acid residues.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human NT-3 Categories Neurotrophic Growth Factors, Recombinant Proteins

Product Details

Product Specifications Species Human Published species Human, Mouse, Rat Expression System E. coli Amino acid sequence MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT Molecular weight 27.2 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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