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CultureGro™ Basic FGF 146 (a.a.)

CultureGro™ Basic FGF 146 (a.a.)

FGF-basic stands as one of the 23 recognized members within the FGF family. These proteins hold pivotal roles in prenatal development, postnatal growth, and tissue regeneration by fostering cellular proliferation and differentiation. FGF-basic, specifically, serves as a non-glycosylated growth factor with a penchant for heparin binding. Its expression spans across various tissues including the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells, and endothelial cells. FGF-basic transmits signals through FGFR 1b, 1c, 2c, 3c, and 4 receptors. The recombinant form of Human FGF-basic, comprised of 146 amino acid residues, yields a 16.4 kDa protein.

$200.00$1,100.00

SKU CultureGro™ Basic FGF 146 (a.a.) Categories ,

Product Details

Product Specifications

Species Human
Published species
Human, Mouse
Expression System E. coli
Amino acid sequence
PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
Molecular weight 16.4 kDa
Class Recombinant
Type Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration <0.1 EU/µg Activity Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C