CultureGro™ Human BMP-4

Name: CultureGro™ Human BMP-4 - Cell Culture Collective
SKU: CultureGro™ Human BMP-4
Availability: InStock

$500.00

Bone morphogenetic proteins (BMPs) belong to the TGF-β superfamily, a group of structurally related signaling proteins. This superfamily is widely distributed in the body and plays diverse roles during prenatal and postnatal life. Like BMP-7, BMP-4 contributes significantly to bone and cartilage development and maintenance. Reduced BMP-4 expression is linked to various bone disorders, including Fibrodysplasia Ossificans Progressiva, an inherited condition.

E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, corresponding to amino acids 303-408 of the full-length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human BMP-4 Categories Recombinant Proteins, TGF-Betas

Product Details

Product Specifications Species Human Published species Human, Mouse, Rat Expression System E.Coli Amino acid sequence KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR Molecular weight 23.9 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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