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FGF-10 is a growth factor within the FGF family that binds to heparin. Proteins in this family are pivotal during prenatal development, postnatal growth, and tissue regeneration by stimulating cellular proliferation and differentiation. FGF-10 shares close relation to KGF/FGF-7 and is prominently expressed during development, particularly in adult lungs. Its signaling occurs through FGFR 2b. Recombinant Human FGF-10 is a protein weighing 19.3 kDa and comprising 170 amino acid residues.
Product Specifications
Species: Human
Published Species: Human, Mouse
Expression System: E.Coli
Amino Acid Sequence: MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Molecular Weight: 19.3 kDa
Class: Recombinant
Type: Protein
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses
Endotoxin concentration: <0.1 EU/µg
Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.5-15.0 ng/ml.
Form: Lyophilized
Contains No Preservative
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