CultureGro™ Human Beta-NGF Recombinant Protein Animal Free
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.
$1,000.00
CultureGro™ Human Beta-NGF Recombinant Protein Animal Free
Species: Human
Published species: Human, Rat
Expression System: E. coli
Amino acid sequence:
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
Molecular weight: 27 kDa
Class: Recombinant
Type: Protein
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration: <0.1 EU/µg
Activity: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
Conjugate: Unconjugated
Form: Lyophilized
Purification: HPLC, SDS-PAGE
Contains no preservative
Storage conditions: -20°C
CAUTION: For Research Use Only. Not for use in diagnostic procedures.
With over 20 years of experience in the life science industry, we work hard to bring our customers the highest quality and most relevant products and services. We specialize in cell culture and diagnostic processed serum, cholesterol concentrates, and purified proteins.
