CultureGro™ Human MCSF Recombinant Protein, Animal-Free

M-CSF (Macrophage Colony-Stimulating Factor) is a powerful hematopoietic agent produced by various cell types, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts, and osteoblasts. It stands as a critical controller of the proliferation, differentiation, and survival of blood monocytes, tissue macrophages, and their precursor cells. M-CSF has demonstrated significant influence in regulating skin thickness and fertility, marking its versatility. Clinically, M-CSF is deployed in the management of infections, cancer, and atherosclerosis, proving instrumental in hastening hematopoietic recovery following bone marrow transplants. While Human M-CSF shows efficacy in murine models, its murine counterpart does not affect human cells, highlighting species-specific responses. Recombinant Human M-CSF, a 36.8 kDa homodimeric protein, is composed of two polypeptide subunits, each with 159 amino acids, showcasing the intricate design of this biologically essential molecule.