CultureGro™ Human IFN gamma

Name: CultureGro™ Human IFN gamma - Cell Culture Collective
SKU: CultureGro™ Human IFN gamma
Availability: InStock

$121.00

IFN-γ, an acid-labile interferon, is produced by CD4 and CD8 T lymphocytes as well as activated NK cells. Its receptors are widespread in immune cells, triggering an increase in class I MHC protein surface expression upon IFN-γ signaling. This enhancement aids in antigen presentation to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, B and T lymphocytes involved in antigen recognition, plays a crucial role in regulating the antigen-specific phases of the immune response. Moreover, IFN-γ stimulates various functions in lymphoid cells, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Notably, Human IFN-γ is species-specific and exhibits biological activity exclusively in Human and primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein composed of 144 amino acid residues.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human IFN gamma Categories Interferons, Recombinant Proteins

Product Details

Product Specifications Species Human Published species Bacteria, Fish, Human, Mouse, Rat, Virus Expression System E. coli Amino acid sequence MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ Molecular weight 16.8 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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