CultureGro™ Human IL-15

Name: CultureGro™ Human IL-15 - Cell Culture Collective
SKU: CultureGro™ Human IL-15
Availability: InStock

$500.00

IL-15 serves as an immunomodulatory cytokine that triggers the growth of T lymphocytes, sharing numerous traits with IL-2. Its primary effects are directed towards T cells, aiding in their development, longevity, and activation. Moreover, IL-15 plays a crucial role in nurturing and activating natural killer (NK) cells. Elevated IL-15 levels have been associated with conditions such as rheumatoid arthritis, inflammatory bowel disease, and diseases linked to retroviruses like HIV and HTLV-I.

In experiments, Human IL-15 has demonstrated biological activity on mouse cells, notably by stimulating the dose-dependent proliferation of mouse CTLL cells. This recombinant protein, consisting of 115 amino acid residues and weighing 12.9 kDa, mirrors these functions.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human IL-15 Categories Cytokines, Recombinant Proteins

Product Details

Product Specifications Species Human Published species Hamster, Human, Mouse Expression System E. coli Amino acid sequence MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS Molecular weight 12.9 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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