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$375.00
CultureGro™ Human IL-3 Recombinant Protein, Animal-Free
IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
CultureGro™ Human IL-3 Recombinant Protein, Animal-Free
Species: Human
Published species: Human, Mouse
Expression System: E. coli
Amino acid sequence:
APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
Molecular weight: 15 kDa
Class: Recombinant
Type: Protein
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration: <0.1 EU/µg
Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Conjugate: Unconjugated
Form Lyophilized
Purification: HPLC, SDS-PAGE
Contains no preservative
Storage conditions: -20°C
CAUTION: For Research Use Only. Not for use in diagnostic procedures.
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