$550.00
CultureGro™ Human MCSF Recombinant Protein, Animal-Free
M-CSF (Macrophage Colony-Stimulating Factor) is a powerful hematopoietic agent produced by various cell types, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts, and osteoblasts. It stands as a critical controller of the proliferation, differentiation, and survival of blood monocytes, tissue macrophages, and their precursor cells. M-CSF has demonstrated significant influence in regulating skin thickness and fertility, marking its versatility. Clinically, M-CSF is deployed in the management of infections, cancer, and atherosclerosis, proving instrumental in hastening hematopoietic recovery following bone marrow transplants. While Human M-CSF shows efficacy in murine models, its murine counterpart does not affect human cells, highlighting species-specific responses. Recombinant Human M-CSF, a 36.8 kDa homodimeric protein, is composed of two polypeptide subunits, each with 159 amino acids, showcasing the intricate design of this biologically essential molecule.
With over 20 years of experience in the life science industry, we work hard to bring our customers the highest quality and most relevant products and services. We specialize in cell culture and diagnostic processed serum, cholesterol concentrates, and purified proteins.