CultureGro™ Human Activin-A

Name: CultureGro™ Human Activin-A - Cell Culture Collective
SKU: CultureGro™ Human Activin-A
Availability: InStock

$495.00

CultureGro™ Human Activin-A Recombinant Protein Animal Free

Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in Human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

Volume

100ug
1mg
500ug
50ug

Clear

SKU CultureGro™ Human Activin-A Categories Recombinant Proteins, TGF-Betas

Product Details

CultureGro™ Human Activin-A Recombinant Protein Animal Free Species: Human, Mouse, Rat Published species: Human, Mouse, Rat Expression System: E. coli Amino acid sequence: GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS Molecular weight: 26 kDa Class: Recombinant Type: Protein Purity: ≥ 97% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration: <0.1 EU/µg Activity: Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg. Conjugate: Unconjugated Form: Lyophilized Purification: HPLC, SDS-PAGE Contains no preservative Storage conditions: -20°C CAUTION: For Research Use Only. Not for use in diagnostic procedures.

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