CultureGro™ Human IL-3

$375.00

CultureGro™ Human IL-3 Recombinant Protein, Animal-Free

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.

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Product Details

CultureGro™ Human IL-3 Recombinant Protein, Animal-Free Species: Human Published species: Human, Mouse Expression System: E. coli Amino acid sequence: APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF Molecular weight: 15 kDa Class: Recombinant Type: Protein Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration: <0.1 EU/µg Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg. Conjugate: Unconjugated Form Lyophilized Purification: HPLC, SDS-PAGE Contains no preservative Storage conditions: -20°C CAUTION: For Research Use Only. Not for use in diagnostic procedures.

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