CultureGro™ Basic FGF 146 (a.a.)

$200.00

FGF-basic stands as one of the 23 recognized members within the FGF family. These proteins hold pivotal roles in prenatal development, postnatal growth, and tissue regeneration by fostering cellular proliferation and differentiation. FGF-basic, specifically, serves as a non-glycosylated growth factor with a penchant for heparin binding. Its expression spans across various tissues including the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells, and endothelial cells. FGF-basic transmits signals through FGFR 1b, 1c, 2c, 3c, and 4 receptors. The recombinant form of Human FGF-basic, comprised of 146 amino acid residues, yields a 16.4 kDa protein.

SKU CultureGro™ Basic FGF 146 (a.a.) Categories ,

Product Details

Product Specifications Species Human Published species Human, Mouse Expression System E. coli Amino acid sequence PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS Molecular weight 16.4 kDa Class Recombinant Type Protein Purity ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration <0.1 EU/µg Activity Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10^7 units/mg. Conjugate Unconjugated Form Lyophilized Contains no preservative Storage conditions -20°C

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