CultureGro™ Human Beta-NGF

$1,000.00

CultureGro™ Human Beta-NGF Recombinant Protein Animal Free

β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.

SKU CultureGro™ Human Beta-NGF Categories ,

Product Details

CultureGro™ Human Beta-NGF Recombinant Protein Animal Free Species: Human Published species: Human, Rat Expression System: E. coli Amino acid sequence: SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA Molecular weight: 27 kDa Class: Recombinant Type: Protein Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Endotoxin concentration: <0.1 EU/µg Activity: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg. Conjugate: Unconjugated Form: Lyophilized Purification: HPLC, SDS-PAGE Contains no preservative Storage conditions: -20°C CAUTION: For Research Use Only. Not for use in diagnostic procedures.

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