FGF-8 (FGF-8b) is a growth factor within the FGF family that binds to heparin. Proteins in this family are crucial for prenatal development, postnatal growth, and the regeneration of various tissues by stimulating cellular proliferation and differentiation. There are four known alternatively spliced forms of FGF-8: FGF-8A, FGF-8B, FGF-8E, and FGF-8F. Human and murine FGF-8A and FGF-8B are identical, while human and mouse FGF-8E and FGF-8F share 98% identity. FGF-8 targets mammary carcinoma cells and other cells expressing FGF receptors. Recombinant Human/Murine FGF-8 (FGF-8b) is a protein weighing 22.5 kDa and composed of 194 amino acid residues.
$320.00
Product Specifications
Species Human
Published Species Human, Mouse
Expression System E.Coli
Amino Acid Sequence MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR
Molecular Weight 22.5 kDa
Class Recombinant
Type Protein
Purity ≥ 98% by SDS-PAGE gel and HPLC analyses
Endotoxin concentration <0.1 EU/µg
Activity Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 2.0-4.0 ng/ml.
Form Lyophilized
Contains No Preservative
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