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SmartMCs P2 Microcarrier for Cell Culture

A plant-based core that dissolves fast and gives you a coating choice. P2 is built for teams that need clean harvest and either standard or xeno-free formats.

Plant-based dissolvable microcarriers with Animal or Xeno-Free Coating, dissolving in about 10 minutes for clean, filtration-free harvest.

Product Details

P2 dissolvable microcarriers are made from a plant-based biopolymer core, coated with either a bovine gelatin/collagen (Animal Coating) or a Xeno-Free Coating. Smart MCs is also developing a novel peptide-based coating for P2.

The microcarriers dissolve through a controlled step using TrypLE and Smart MCs’ proprietary P2 Dissolving Buffer, typically about 10 minutes, removing the need to filter cells out after expansion.

In evaluations using C2C12 myoblasts, P2 showed greater than 90% cell attachment within 24 hours, expansion of up to 30-fold over 7 days depending on seeding density, cell densities reaching approximately 1 × 10 cells/mL, recovery approaching 100% following dissolution, and post-harvest viability exceeding 90%, with differentiation capacity maintained.

KEY FEATURES

  • Plant-based core with Animal Coating or Xeno-Free Coating.
  • Fastest dissolution of the three platforms, about 10 minutes with TrypLE and P2 Dissolving Buffer.
  • Soft, Medium, and Hard stiffness grades, customizable 3–100 kPa.
  • Rapid dissolution simplifies downstream processing and cell recovery.
  • Research grade, Food Grade, and GMP-compliant options available.
  • Certificate of Analysis provided with every order.

APPLICATIONS

  • Mesenchymal stem cells (MSCs).
  • Fibroblasts and myoblasts.
  • Virus production.
  • Secretome production.
  • Cell therapy workflows.

SPECIFICATIONS

Material Plant-based biopolymer core, Animal or Xeno-Free Coating
Format Freeze-dried powder, supplied by surface area (cm²)
Stiffness Soft, Medium, Hard, customizable 3–100 kPa
Particle size Approx. 160–270 µm, customizable
Dissolvability Yes, TrypLE + P2 Dissolving Buffer, about 10 minutes
Sterilization Autoclave, heat, or gamma irradiation
Grade Research, Food Grade, GMP-compliant options
Certificate of Analysis Provided

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