KGF (FGF-7), also known as Keratinocyte Growth Factor, is a member of the FGF family, which comprises 23 known proteins. This family of proteins holds a critical position in prenatal development, postnatal growth, and the regeneration of various tissues, achieving this through the promotion of cellular proliferation and differentiation. Specifically, KGF (FGF-7) acts as a mitogenic factor targeting epithelial cells and keratinocytes.
KGF (FGF-7) transmits its signals via FGFR 2b and contributes significantly to kidney and lung development, as well as angiogenesis and wound healing processes. The recombinant Human KGF (FGF-7) is an 18.9 kDa protein composed of 163 amino acid residues.
$585.00 – $4,950.00
Product Specifications
Species Human
Published Species Human, Mouse, Rat
Expression System E.Coli
Amino Acid Sequence CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT
Molecular Weight 18.9 kDa
Class Recombinant
Type Protein
Purity ≥ 98% by SDS-PAGE gel and HPLC analyses
Endotoxin concentration <0.1 EU/µg
Activity Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.1-15 ng/ml.
Form Lyophilized
Contains No Preservative
Storage conditions -20°C
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